Selective cleavage of the β-O-4 ether bond of lignin to produce aromatics is one of the most important topics of the sustainable production of chemicals from biomass. We demonstrate a simple system for C α -C β bond cleavage of a β-O-4 ketone structured lignin model compound (LMC) by H 2 O 2 in formic acid under metal catalyst-free conditions. In the system simply with H 2 O 2 , formic acid, and mineral acid catalyst, over 90% of product yield could be achieved in 6 h at room temperature. The reaction proceeds through the classic Baeyer-Villiger oxidation (BVO) and the in situ generated performic acid is the key oxidant. The cleavage of alcohol LMC by the present method in a two-step process is also successfully demonstrated.

中文翻译：

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甲酸中H2O2对木质素模型化合物的无金属催化剂的氧化CC键裂解。

木质素的β-O-4醚键的选择性裂解以产生芳族化合物是从生物质可持续生产化学品的最重要主题之一。我们展示了一个简单的系统，用于在无金属催化剂的条件下，通过甲酸中的H 2 O 2来对β-O-4酮结构化的木质素模型化合物（LMC）进行Cα-Cβ键裂解。在仅使用H 2 O 2，甲酸和无机酸催化剂的系统中，室温下6小时内即可达到90％以上的产品收率。该反应通过经典的Baeyer-Villiger氧化（BVO）进行，并且原位生成的甲酸是关键氧化剂。还成功地证明了通过本发明方法在两步法中裂解醇LMC。