Polysomnographic studies have been conducted to explore sleep changes in Parkinson's disease (PD), but the relationships between sleep disturbances and PD are imperfectly understood. We conducted a systematic review of the literature exploring polysomnographic differences between PD patients and controls in EMBASE, MEDLINE, All EBM databases, CINAHL, and PsycIFNO. 67 studies were identified for systematic review, 63 of which were used for meta-analysis. Meta-analyses revealed significant reductions in total sleep time, sleep efficiency, N2 percentage, slow wave sleep, rapid eye movement sleep (REM) percentage, and increases in wake time after sleep onset, N1 percentage, REM latency, apnea hypopnea index, and periodic limb movement index in PD patients compared with controls. There were no remarkable differences in sleep continuity or sleep architecture between PD patients with and without REM sleep behavior disorder (RBD). Our study suggests that PD patients have poor sleep quality and quantity. Sex, age, disease duration, presence of RBD, medication status, cognitive impairment, and adaptation night are factors that contributed to heterogeneity between studies.

已经进行了多导睡眠图研究来探索帕金森氏病（PD）的睡眠变化，但对睡眠障碍与PD之间的关系还没有完全了解。我们对EMBASE，MEDLINE，所有EBM数据库，CINAHL和PsycIFNO中PD患者与对照之间多导睡眠图差异的文献进行了系统的综述。确定了67项研究进行系统评价，其中63项用于荟萃分析。荟萃分析显示，总睡眠时间，睡眠效率，N2百分比，慢波睡眠，快速眼动睡眠（REM）百分比显着减少，并且睡眠发作后醒来时间，N1百分比，REM潜伏期，呼吸暂停低通气指数和PD患者的定期肢体运动指数与对照组相比。有和没有REM睡眠行为障碍（RBD）的PD患者之间的睡眠连续性或睡眠结构没有显着差异。我们的研究表明，PD患者的睡眠质量和数量均较差。性别，年龄，疾病持续时间，RBD的存在，用药状况，认知障碍和适应夜均是导致研究之间异质性的因素。