Abstract

This work reports studies on the production of eugenol-loaded microspheres by solvent evaporation method, targeted for incorporation into textile substrates, using different cellulose derivatives: ethyl cellulose, cellulose acetate (CA), cellulose butyrate acetate, and cellulose acetate phthalate. The microspheres were evaluated in terms of size, shape, thermal stability, encapsulation efficiency, and eugenol kinetics release. CA-based microspheres proved to be the best, thus being selected for subsequent experiments. Comparable properties of the CA-based microspheres were achieved ongoing from 100 mL to higher batch volumes (up to 2000 mL). The eugenol-loaded microspheres were successfully incorporated into cotton fabrics using a padding technique, confirmed by FE-SEM. Eugenol release profiles from the impregnated textiles demonstrated a slow and controlled release (less than 20% of the encapsulated amount over 90 days). The developed microspheres demonstrated to be the most promising for the retention and protection of hydrophobic active compounds for possible textile applications.

Graphic abstract

摘要

这项工作报告了通过溶剂蒸发法生产丁香酚微球的研究，该方法旨在使用不同的纤维素衍生物（乙基纤维素，醋酸纤维素（CA），醋酸丁酸纤维素和邻苯二甲酸醋酸纤维素）并入纺织品基质中。在尺寸，形状，热稳定性，包封效率和丁香酚动力学释放方面评估了微球。基于CA的微球被证明是最好的，因此被选作后续实验。从100毫升到更高的批次体积（最高2000毫升），CA基微球的可比性能得以实现。FE-SEM证实，使用填充技术将负载丁香酚的微球成功掺入棉织物中。从浸渍的纺织品中丁香酚的释放曲线显示出缓慢且受控的释放（在90天内不到封装量的20％）。事实证明，开发的微球在疏水性活性化合物的保留和保护方面最有希望，可用于可能的纺织品应用。

图形摘要