BACKGROUND Cone Beam Computed Tomography (CBCT) is a reliable radiographic modality to assess trabecular bone microarchitecture. The aim of this study was to determine the effect of CBCT image reconstruction parameters, namely, the threshold value and reconstruction voxel size, on trabecular bone microstructure assessment. METHODS Five sectioned maxilla of adult Dorper male sheep were scanned using a CBCT system with a resolution of 76 μm3 (Kodak 9000). The CBCT images were reconstructed using different reconstruction parameters and analysed. The effect of reconstruction voxel size (76, 100 and 200 μm3) and threshold values (±15% from the global threshold value) on trabecular bone microstructure measurement was assessed using image analysis software (CT analyser version 1.15). RESULTS There was no significant difference in trabecular bone microstructure measurement between the reconstruction voxel sizes, but a significant difference (Tb.N = 0.03, Tb.Sp = 0.04, Tb.Th = 0.01, BV/TV = 0.00) was apparent when the global threshold value was decreased by 15%. CONCLUSIONS Trabecular bone microstructure measurements are not compromised by changing the CBCT reconstruction voxel size. However, measurements can be affected when applying a threshold value of less than 15% of the recommended global value.

中文翻译：

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重建参数对绵羊锥束CT小梁骨显微结构定量的影响。

背景技术锥形束计算机断层摄影术（CBCT）是评估小梁骨微结构的可靠的放射线照相形式。这项研究的目的是确定CBCT图像重建参数（即阈值和重建体素大小）对小梁骨微结构评估的影响。方法使用分辨率为76μm3（Kodak 9000）的CBCT系统扫描成年杜泊公羊的五节上颌骨。使用不同的重建参数重建CBCT图像并进行分析。使用图像分析软件（CT分析仪1.15版）评估了重建体素大小（76、100和200μm3）和阈值（相对于全局阈值的±15％）对小梁骨微结构测量的影响。结果重建体素大小之间的小梁骨微观结构测量没有显着差异，但是当显像时明显差异（Tb.N = 0.03，Tb.Sp = 0.04，Tb.Th = 0.01，BV / TV = 0.00）。全球阈值降低了15％。结论改变CBCT重建体素大小不会影响小梁的骨微结构测量。但是，当阈值小于建议的全局值的15％时，测量可能会受到影响。结论改变CBCT重建体素大小不会影响小梁的骨微结构测量。但是，当阈值小于建议的全局值的15％时，测量可能会受到影响。结论改变CBCT重建体素大小不会影响小梁的骨微结构测量。但是，当阈值小于建议的全局值的15％时，测量可能会受到影响。