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Know Your Model: A knockout does not always make a null.
Lab Animal ( IF 6.9 ) Pub Date : 2020-02-10 , DOI: 10.1038/s41684-020-0486-4
Susan M Bello 1 , Michelle N Perry 1 , Cynthia L Smith 1
Affiliation  

Creating a null mutation of a gene is a powerful way to examine gene function, but knocking out part of a gene does not always result in a null allele.

中文翻译:

知道您的模型:剔除并不总是为空。

创建基因的无效突变是检查基因功能的有效方法,但是敲除基因的一部分并不一定会导致无效等位基因。
更新日期:2020-02-10
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