Unsaturated fatty esters can be easily transformed into ketoesters through a two-step process. The highly efficient epoxidation is carried out with tert-butyl hydroperoxide (TBHP) in α,α,α-trifluorotoluene (TFT) using a Ti–silica heterogeneous catalyst. The formed epoxide is easily rearranged by a heterogeneous Brønsted acid, with Nafion–silica SAC13 as the most efficient one. Both reactions can be combined in a tandem process, with separation of the Ti–silica catalyst by filtration from the reaction medium and addition of the second acid catalyst to perform the second reaction. Each catalyst is separated individually and can be reused, with or without re-activation, under the same conditions to maximize the productivity.

中文翻译：

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串联环氧化-非均相催化重排合成脂肪酮酯

不饱和脂肪酸酯可通过两步过程轻松转化为酮酸酯。高效的环氧化反应是使用Ti-二氧化硅非均相催化剂在α，α，α-三氟甲苯（TFT）中使用氢过氧化叔丁基（TBHP）进行的。形成的环氧化物很容易被异质布朗斯台德酸重排，Nafion-silica SAC13是最有效的环氧化物。可以将两个反应串联在一起，通过过滤从反应介质中分离出Ti-二氧化硅催化剂，然后加入第二种酸催化剂进行第二种反应。每种催化剂都可以单独分离，可以在相同条件下重复使用，无论是否进行再活化，以使生产率最大化。