当前位置: X-MOL 学术J. Biomed. Mater. Res. Part A › 论文详情
Cell alignment by smectic liquid crystal elastomer coatings with nanogrooves.
Journal of Biomedical Materials Research Part A ( IF 3.525 ) Pub Date : 2020-02-08 , DOI: 10.1002/jbm.a.36896
Greta Babakhanova,Jess Krieger,Bing-Xiang Li,Taras Turiv,Min-Ho Kim,Oleg D Lavrentovich

Control of cells behavior through topography of substrates is an important theme in biomedical applications. Among many materials used as substrates, polymers show advantages since they can be tailored by chemical functionalization. Fabrication of polymer substrates with nano- and microscale topography requires processing by lithography, microprinting, etching, and so forth. In this work, we introduce a different approach based on anisotropic elastic properties of polymerized smectic A (SmA) liquid crystal elastomer (LCE). When the SmA liquid crystal coating is deposited onto a substrate with planar alignment of the molecules, it develops nanogrooves at its free surface. After photopolymerization, these nanogrooves show an excellent ability to align human dermal fibroblasts over large areas. The alignment quality is good for both bare SmA LCE substrates and for substrates coated with fibronectin. The SmA LCE nano-topographies show a high potential for tissue engineering.
更新日期:2020-03-19

 

全部期刊列表>>
欢迎访问IOP中国网站
自然职场线上招聘会
GIANT
产业、创新与基础设施
自然科研线上培训服务
材料学研究精选
胸腔和胸部成像专题
屿渡论文,编辑服务
何川
苏昭铭
陈刚
姜涛
李闯创
李刚
北大
跟Nature、Science文章学绘图
隐藏1h前已浏览文章
中洪博元
课题组网站
新版X-MOL期刊搜索和高级搜索功能介绍
ACS材料视界
x-mol收录
上海纽约大学
张健
陈芬儿
厦门大学
李祥
吉林大学
卓春祥
张昊
杨中悦
试剂库存
天合科研
down
wechat
bug