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Ion recognition and fluorescent imaging of conjugated polymer fluorescent probes for Fe(III)
Bulletin of Materials Science ( IF 1.8 ) Pub Date : 2020-02-10 , DOI: 10.1007/s12034-019-2029-4
Lei Zheng , Zhao Cheng , Hao HE , Hao Xu , Fei Liang , Long Pang

Novel polymer fluorescent probes for Fe(III) were synthesized to achieve a steady combination of ferric ions. In the Schiff base reaction of probes’ synthetic process, o -, m - and p -phenylenediamine were respectively introduced to result in a series of new conjugated polymer fluorescent probes. Analyses on optical properties of the probes and probe-Fe(III) characteristic recognition through FS showed an application of the conjugated probes in quantitative identification and detection of Fe(III) with quick responses. Fluorescent imaging of the probes and probe-Fe(III) in living cells in vitro revealed low toxicity of the probes and predicted the probes’ further application for instant $$\text {Fe}^{{3+}}$$ Fe 3 + detection in clinical diagnosis and dynamic tracing of $$\text {Fe}^{{3+}}$$ Fe 3 + in biological systems.

中文翻译:

Fe(III) 共轭聚合物荧光探针的离子识别和荧光成像

合成了用于 Fe(III) 的新型聚合物荧光探针,以实现三价铁离子的稳定组合。在探针合成过程的席夫碱反应中,分别引入邻苯二胺、间苯二胺和对苯二胺,生成了一系列新型共轭聚合物荧光探针。通过FS对探针的光学性质和探针-Fe(III)特征识别的分析表明,共轭探针在快速响应的Fe(III)定量鉴定和检测中的应用。体外活细胞中探针和探针-Fe(III) 的荧光成像揭示了探针的低毒性,并预测了探针在即刻 $$\text {Fe}^{{3+}}$$ Fe 3 中的进一步应用+ 在生物系统中 $$\text {Fe}^{{3+}}$$ Fe 3 + 的临床诊断和动态追踪中的检测。
更新日期:2020-02-10
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