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Immune Checkpoint Inhibition in Prostate Cancer.
Trends in Cancer ( IF 18.4 ) Pub Date : 2020-02-06 , DOI: 10.1016/j.trecan.2020.01.003
Lowell Thorndike Nicholson 1 , Lawrence Fong 2
Affiliation  

Although immunotherapy has proved to be effective in a variety of cancer subtypes, the role of immune checkpoint inhibition in the treatment of prostate cancer remains unclear. Here we review results from the latest clinical trials and discuss data suggesting that certain genetic mutations may confer increased sensitivity to immune checkpoint blockade.



中文翻译:

前列腺癌的免疫检查点抑制。

尽管免疫疗法已被证明对多种癌症亚型有效,但免疫检查点抑制在前列腺癌治疗中的作用仍不清楚。在这里,我们回顾了最新临床试验的结果,并讨论了表明某些基因突变可能赋予免疫检查点封锁更高敏感性的数据。

更新日期:2020-02-06
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