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Atherosclerosis Immunoimaging by Positron Emission Tomography.
Arteriosclerosis, Thrombosis, and Vascular Biology ( IF 8.7 ) Pub Date : 2020-02-06 , DOI: 10.1161/atvbaha.119.313455
Carlos Pérez-Medina 1, 2 , Zahi A Fayad 2 , Willem J M Mulder 2, 3
Affiliation  

The immune system's role in atherosclerosis has long been an important research topic and is increasingly investigated for therapeutic and diagnostic purposes. Therefore, noninvasive imaging of hematopoietic organs and immune cells will undoubtedly improve atherosclerosis phenotyping and serve as a monitoring method for immunotherapeutic treatments. Among the available imaging techniques, positron emission tomography's unique features make it an ideal tool to quantitatively image the immune response in the context of atherosclerosis and afford reliable readouts to guide medical interventions in cardiovascular disease. Here, we summarize the state of the art in the field of atherosclerosis positron emission tomography immunoimaging and provide an outlook on current and future applications.

中文翻译:

正电子发射断层扫描对动脉粥样硬化进行免疫成像。

长期以来,免疫系统在动脉粥样硬化中的作用一直是一个重要的研究课题,并且出于治疗和诊断目的,人们对其进行了越来越多的研究。因此,造血器官和免疫细胞的无创成像无疑将改善动脉粥样硬化的表型,并作为免疫疗法治疗的监测方法。在可用的成像技术中,正电子发射断层扫描的独特功能使其成为定量成像动脉粥样硬化情况下的免疫反应并提供可靠的读数以指导心血管疾病医疗干预的理想工具。在这里,我们总结了动脉粥样硬化正电子发射断层扫描免疫成像领域的最新技术,并对当前和将来的应用提供了展望。
更新日期:2020-03-26
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