The reaction of pyrimidine based electron-rich heterocyclic thiophene pyrazoles and halide bridged arene d⁶ metal precursors yielded a series of mononuclear and dinuclear half sandwich d⁶ metal complexes. Mononuclear and dinuclear complexes formed by the ratio-based reaction between ligand and metal precursor. All these cationic complexes have been characterized by IR, UV–Vis, ¹H NMR, ¹³C NMR spectroscopic techniques. Complex 5 has been established by single-crystal analysis. X-ray diffraction studies revealed the formation of mononuclear and dinuclear complexes and suggest that the vicinity around the metal atom is distorted octahedral. An in vitro study to screen the antibacterial potential of these complexes against pathogenic bacteria, S. aureus, K. pneumoniae, and E. coli was addressed. All the complexes display a better zone of inhibitions for both Gram-positive (S. aureus) and Gram-negative strains (K. pneumoniae, and E. coli). The minimum inhibitory concentrations (MICs) for the most active complex ranged from 0.125 to 0.25 mg/ml for S. aureus and Klebsiella Pneumoniae and 0.25–0.5 mg/ml for E. coli.

基于嘧啶的富含电子的杂环噻吩吡唑与卤化物桥联的芳烃d ⁶金属前体的反应产生了一系列单核和双核半夹心d ⁶金属络合物。单核和双核配合物是由配体和金属前体之间基于比率的反应形成的。所有这些阳离子配合物均已通过IR，UV-Vis，¹ H NMR，¹³ C NMR光谱技术进行了表征。通过单晶分析建立了络合物5。X射线衍射研究揭示了单核和双核配合物的形成，并表明金属原子周围的附近是扭曲的八面体。一种在体外筛选这些复合物对病原菌，金黄色葡萄球菌，肺炎克雷伯菌和大肠杆菌的抗菌潜能的研究已得到解决。所有复合物对革兰氏阳性菌株（金黄色葡萄球菌）和革兰氏阴性菌株（肺炎克雷伯菌和大肠杆菌）均显示出更好的抑制区。对于金黄色葡萄球菌和肺炎克雷伯菌而言，对活性最高的复合物的最低抑菌浓度（MIC）为0.125至0.25 mg / ml，而对于大肠杆菌，则为0.25–0.5 mg / ml 。