With recent advances in diagnostic imaging, pancreatic neuroendocrine neoplasm (PNEN) have been found in small size, and its handling has changed depending on grade according to the Ki-67 index and mitotic rate, based on the 2017 World Health Organization classification. Of note, high-grade well-differentiated NEN is defined as neuroendocrine tumor (NET) and divided into grades 1 to 3, with PNET showing values of >20% for both Ki-67 index and mitotic index classified as grade 3 by the latest WHO classification.

中文翻译：

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EUS 引导下的小 PNEN 乙醇消融

随着诊断成像的最新进展，胰腺神经内分泌肿瘤 (PNEN) 已被发现体积较小，并且根据 2017 年世界卫生组织的分类，根据 Ki-67 指数和有丝分裂率，其处理方式已发生变化。值得注意的是，高级别分化良好的 NEN 被定义为神经内分泌肿瘤 (NET)，分为 1 至 3 级，PNET 显示的 Ki-67 指数和有丝分裂指数的值均 >20%，最新被归类为 3 级。世界卫生组织分类。