Gardenia fruit is widely used in herbal medicine, and it has choleretic, sedative, diuretic, anti-inflammatory, and antipyretic effects.¹ An ingredient of gardenia fruit is attracting attention as a possible cause of mesenteric phlebosclerosis, which is characterized by fibrotic change or calcification of the mesenteric vein and the bronze coloration of the colonic membrane.² Mesenteric phlebosclerosis may cause abdominal pain, stool abnormalities, and bowel obstruction, but it is often asymptomatic. It is suggested that genipin, a metabolite of geniposide (the major ingredient of gardenia fruit) is involved in the bronze coloration. Herein, we describe a patient who took the extract of gardenia fruit for 7 years, developed skin pigmentation complicated with mesenteric phlebosclerosis.

ia子果实被广泛用于草药中，具有利胆，镇静，利尿，消炎和解热的作用。¹ garden子果实的一种成分引起了人们的关注，它可能是引起肠系膜静脉硬化的原因，其特征是肠系膜纤维化或钙化，结肠膜呈青铜色。²肠系膜静脉硬化症可引起腹痛，大便异常和肠梗阻，但通常无症状。有人指出，古尼平是，子糖苷的一种代谢产物（of子果实的主要成分），可能与古铜色有关。在本文中，我们描述了一位服用took子果实提取物7年，皮肤色素沉着并伴有肠系膜静脉硬化的患者。