Gangliogliomas are rare tumors of the central nervous system. They can occur anywhere in the central nervous system but are most commonly located in the temporal lobe and are mainly found in children. Anaplastic ganglioglioma can result from either de novo or transformation of a pre-existing lesion. We report a case of de novo anaplastic ganglioglioma in the parieto occipital region, which is a rare location. A 34-year-old lady presented with features of raised intracranial pressure (ICP) with right side hemiparesis. Contrast-enhanced magnetic resonance imaging (CEMRI) of the brain showed well-defined intense heterogenously enhancing solid cystic mass lesion 5.3 × 5.2 cm in the left parieto occipital region with mass effect and midline shift. Intraoperatively, a cystic mass lesion with reddish brown nodule was seen in the left occipital lobe. Complete tumor excision was done. Microscopic and IHC examination was suggestive of anaplastic ganglioglioma. The post-operative period was uneventful. The patient received 60-Gy radiotherapy with temozolamide as adjuvant therapy, and repeat imaging showed no tumor recurrence. Anaplastic gangliogliomas are rare tumors with parieto occipital as rare location.

中文翻译：

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神经节胶质瘤罕见部位的一例报道

神经胶质瘤是中枢神经系统的罕见肿瘤。它们可以发生在中枢神经系统的任​​何位置，但最常见于颞叶，主要见于儿童。变性神经节性神经胶质瘤可以由既往病变或从原有病变转变而引起。我们报告了在顶枕区域的一例从头变性间质神经节胶质瘤。一名34岁的女士表现出颅内压升高（ICP）和右侧偏瘫的特征。大脑的对比增强磁共振成像（CEMRI）显示，在左侧顶枕枕部5.3×5.2 cm处，明确定义的强烈异质性增强的固态囊性肿块病灶具有质量效应和中线移位。术中在左侧枕叶见囊肿性肿块，红褐色结节。完成肿瘤切除。镜检和IHC检查提示间变性神经节胶质瘤。术后期间平稳。该患者接受60Gy放射治疗，并用替莫唑胺作为辅助治疗，并且重复成像未见肿瘤复发。间变性神经节胶质瘤是罕见的肿瘤，以顶枕为罕见部位。