Core-shell hydrogel nanocomposite was fabricated by encapsulating a silica-gold nanoshell (SGNS) with poly(N-isopropylacrylamide-co-acrylic acid) (PNIPAM-co-AAc) copolymer. The oleylamine-functionalized SGNS was used as a nanotemplate for the shell-layer growth of hydrogel copolymer. APS (ammonium persulfate) was used as a polymerization initiator to produce a hydrogel-encapsulated SGNS (H-SGNS). The amounts of NIPAM (N-isopropylacrylamide) monomers were optimized to reproduce the hydrogel-encapsulated SGNS. The shell-layer thickness was increased with the increase of polymerization time and no further increase in the shell-layer thickness was clearly observed over 16 h. H-SGNS exhibited the systematic changes of particle size corresponding to the variation of pH and temperature, which was originated from hydrogen-bonding interaction between PNIPAM amide groups and water, as well as electrostatic forces attributed by the ionization of carboxylic groups in acrylic acid.

中文翻译：

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聚（N-异丙基丙烯酰胺-共丙烯酸）水凝胶包封二氧化硅-金纳米​​壳的相对参数贡献

通过用聚（N-异丙基丙烯酰胺-共-丙烯酸）（PNIPAM-共-AAc）共聚物封装二氧化硅-金纳米​​壳（SGNS）来制备核-壳水凝胶纳米复合材料。油胺官能化的SGNS被用作水凝胶共聚物的壳层生长的纳米模板。APS（过硫酸铵）用作聚合引发剂，以生产水凝胶封装的SGNS（H-SGNS）。NIPAM（N对-异丙基丙烯酰胺）单体进行了优化，以复制水凝胶包裹的SGNS。随着聚合时间的增加，壳层厚度增加，并且在16小时内没有明显观察到壳层厚度的进一步增加。H-SGNS表现出与pH和温度变化相对应的系统粒度变化，这是由于PNIPAM酰胺基团与水之间的氢键相互作用以及丙烯酸中羧基的电离作用所产生的静电力。