With the increase in need of ideal bone graft materials, magnesium silicate has been explored as resorbable bioceramics. Calcium phosphate-based bioceramics are well studied and being implemented for several orthopaedic applications as they mimic the chemistry of the natural bone. Although extensively used, these materials do not satisfy all the essential requirements of an ideal temporary bone replacement material. Materials, such as tricalcium phosphate (TCP) and hydroxyapatite (HA), have low solubility and often the resorption rate is quite slow when implanted in vivo. The research on magnesium silicate for bone regenerative application is quite relatively young and a new area compared to traditional calcium phosphate-based materials. Although limited research findings have been reported, it is believed that magnesium silicate-based bioceramics may be an alternative to calcium phosphate for bone tissue engineering applications. Thus in this review, we have highlighted the importance of magnesium silicate bioceramics and compared with existing calcium phosphate ceramics. We have also analysed the future directions and the need for clinical implementations.

中文翻译：

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用于骨再生的硅酸镁生物陶瓷：综述

随着对理想骨移植材料需求的增加，硅酸镁已被探索为可吸收生物陶瓷。以磷酸钙为基础的生物陶瓷经过充分研究，并被用于多种骨科应用，因为它们模仿天然骨骼的化学性质。尽管被广泛使用，但这些材料不能满足理想临时骨替代材料的所有基本要求。诸如磷酸三钙 (TCP) 和羟基磷灰石 (HA) 之类的材料溶解度低，并且在植入体内时吸收速率通常非常慢。与传统的磷酸钙基材料相比，用于骨再生应用的硅酸镁的研究相对较年轻，也是一个新的领域。尽管报道的研究结果有限，相信基于硅酸镁的生物陶瓷可能是骨组织工程应用中磷酸钙的替代品。因此，在这篇综述中，我们强调了硅酸镁生物陶瓷的重要性，并与现有的磷酸钙陶瓷进行了比较。我们还分析了未来的方向和临床实施的需求。