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Epistasis between Phenylethanolamine N-methyltransferase (PNMT) and β2-adrenergic receptor (ADRB2) Influences Extracellular Epinephrine Level and Associates with the Susceptibility to Allergic Asthma
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2020-01-15 , DOI: 10.1111/cea.13552 Yang Yie Sio 1 , Sri Anusha Matta 1 , Yu Ting Ng 1 , Fook Tim Chew 1
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2020-01-15 , DOI: 10.1111/cea.13552 Yang Yie Sio 1 , Sri Anusha Matta 1 , Yu Ting Ng 1 , Fook Tim Chew 1
Affiliation
Reduced extracellular epinephrine level often associates with asthma‐related symptoms; however, the correlation between asthma and genetic variants in genes participating in the epinephrine signalling pathway remains unclear.
中文翻译:
苯乙醇胺 N-甲基转移酶 (PNMT) 和 β2-肾上腺素能受体 (ADRB2) 之间的上位性影响细胞外肾上腺素水平及其与过敏性哮喘易感性的相关性
细胞外肾上腺素水平降低通常与哮喘相关症状有关;然而,哮喘与参与肾上腺素信号通路的基因的遗传变异之间的相关性仍不清楚。
更新日期:2020-01-15
中文翻译:
苯乙醇胺 N-甲基转移酶 (PNMT) 和 β2-肾上腺素能受体 (ADRB2) 之间的上位性影响细胞外肾上腺素水平及其与过敏性哮喘易感性的相关性
细胞外肾上腺素水平降低通常与哮喘相关症状有关;然而,哮喘与参与肾上腺素信号通路的基因的遗传变异之间的相关性仍不清楚。