• Nanosized cytotoxic drug could combat against the autophagy induced by the drug.

• The drug nanorods enabled efficient intracellular delivery of the nucleic acid and the resultant autophagy inhibition in vitro and in vivo, which in turn sensitized the cancer cells to the anti-tumor nanorods.

中文翻译：

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药物纳米棒介导的通过自噬抑制自我致敏的microRNA-101的细胞内递送。

• 纳米细胞毒性药物可以对抗药物诱导的自噬。

• 药物纳米棒能够有效地在细胞内递送核酸，并在体外和体内产生自噬抑制作用，从而使癌细胞对抗肿瘤纳米棒敏感。