The prevalence of sarcopenia is increasing in aging populations, so prevention is critical. Vitamins (A, C, E and carotenoids) modify skeletal muscle via protein and collagen synthesis and anti-inflammatory activities. Previous studies have not investigated intake of these vitamins in relation to sarcopenic indices in both younger and older-aged women. Indices of skeletal muscle mass (as fat-free mass (FFM) relative to body size) were measured using DXA and leg explosive power (LEP) using the Nottingham Power Rig in 2570 women aged 18-79 years. Adjusted measures of skeletal muscle were calculated according to quintiles of vitamin C, E, retinol and carotenoid intake, derived from Food Frequency Questionnaires, after stratification by age. Higher vitamin C intake was associated with significantly higher indices of FFM and LEP, (Q5-Q1 = 2.0-12.8%, P < 0.01-0.02). Intakes of total and individual carotenoids were significantly associated with indices of FFM and LEP (Q5-Q1 = 1.0-7.5%). Vitamin E was significantly associated with FFM% and FFMBMI only. In mutually adjusted analysis with vitamin C, total carotene, vitamin E and protein in the model, the strongest associations were with vitamin C. These associations were stronger in younger women (< 65 years). For the first time, our research shows higher dietary intakes of antioxidant vitamins, particularly vitamin C, is associated with higher skeletal muscle mass and power in free-living women. These findings have relevance for the treatment and prevention of frailty and sarcopenia throughout adulthood.

中文翻译：

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膳食抗氧化剂维生素C，E与类胡萝卜素摄入量和18至79岁女性的肌肉减少指数之间的跨部门关联。

肌肉减少症的患病率在老龄化人群中正在增加，因此预防至关重要。维生素（A，C，E和类胡萝卜素）通过蛋白质和胶原蛋白的合成以及抗炎活性来修饰骨骼肌。以前的研究尚未调查与年轻女性和老年女性的肌肉减少症指数相关的这些维生素的摄入量。在2570名年龄在18-79岁的女性中，使用DXA和使用Nottingham Power Rig的腿部爆发力（LEP）测量了骨骼肌质量（相对于体型的无脂肪质量（FFM））指标。根据年龄分层后，根据食物频率问卷得出的维生素C，E，视黄醇和类胡萝卜素的摄入量的五分位数计算骨骼肌的调整量度。较高的维生素C摄入量与FFM和LEP指数显着较高相关（Q5-Q1 = 2.0-12.8％，P <0.01-0.02）。总和单个类胡萝卜素的摄入量与FFM和LEP指数显着相关（Q5-Q1 = 1.0-7.5％）。维生素E仅与FFM％和FFMBMI显着相关。在模型中与维生素C，总胡萝卜素，维生素E和蛋白质的相互调整分析中，与维生素C的关联最强。这些关联在年轻女性（<65岁）中更强。我们的研究首次显示，饮食中抗氧化剂维生素（尤其是维生素C）的摄入量较高，与自由活动妇女的骨骼肌质量和力量相关。这些发现与整个成年期的虚弱和肌肉减少症的治疗和预防有关。维生素E仅与FFM％和FFMBMI显着相关。在模型中与维生素C，总胡萝卜素，维生素E和蛋白质的相互调整分析中，与维生素C的关联最强。这些关联在年轻女性（<65岁）中更强。我们的研究首次显示，饮食中抗氧化剂维生素（尤其是维生素C）的摄入量较高，与自由活动妇女的骨骼肌质量和力量相关。这些发现与整个成年期的虚弱和肌肉减少症的治疗和预防有关。维生素E仅与FFM％和FFMBMI显着相关。在模型中与维生素C，总胡萝卜素，维生素E和蛋白质的相互调整分析中，与维生素C的关联最强。这些关联在年轻女性（<65岁）中更强。我们的研究首次显示，饮食中抗氧化剂维生素（尤其是维生素C）的摄入量较高，与自由活动妇女的骨骼肌质量和力量相关。这些发现与整个成年期的虚弱和肌肉减少症的治疗和预防有关。我们的研究首次显示，饮食中抗氧化剂维生素（尤其是维生素C）的摄入量较高，与自由活动妇女的骨骼肌质量和力量相关。这些发现与整个成年期的虚弱和肌肉减少症的治疗和预防有关。我们的研究首次显示，饮食中摄入的抗氧化剂维生素（特别是维生素C）的摄入量与自由生活妇女的骨骼肌质量和力量较高有关。这些发现与整个成年期的虚弱和肌肉减少症的治疗和预防有关。