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Wetting ability of human blood in the presence of gold nanoparticles
Gold Bulletin ( IF 2.2 ) Pub Date : 2018-06-12 , DOI: 10.1007/s13404-018-0236-1
L. Torrisi , C. Scolaro , N. Restuccia

Gold nanoparticles are more and more used in bio-medical field for their advantages to be employed as contrast medium for diagnostic images and as targets of disease cells in which thermal-therapy or radiotherapy must be applied. In this contest, a suitable concentration of nanoparticles was added to human blood to study in vitro some physical properties of the treated liquid which is prepared to transport the nanoparticles to the different organs where they can be accumulated by metabolic effects. Measurements indicated that the insertion of gold nanoparticles in the human blood improves the blood wetting ability. In particular, the wetting ability of the blood containing or not gold nanoparticles, with respect to different biocompatible solid surfaces, was investigated. Also, the density, tension surface, and viscosity of the solution at room temperature were measured. Results demonstrated that the introduction of gold nanoparticles in the blood, with size distribution centered at about 50 nm, generally improves the wetting ability and changes other properties of the solution, due to the different distributions of the cohesion and adhesion forces.

中文翻译:

金纳米粒子存在时人体血液的润湿能力

金纳米粒子因其作为诊断图像的造影剂和必须应用热疗法或放射疗法的疾病细胞的靶标的优势而越来越多地用于生物医学领域。在本次比赛中,将适当浓度的纳米颗粒添加到人体血液中,以在体外研究处理过的液体的一些物理特性,该液体准备将纳米颗粒输送到不同的器官,在那里它们可以通过代谢作用积累。测量表明,在人体血液中插入金纳米颗粒可提高血液润湿能力。特别地,研究了含有或不含金纳米颗粒的血液对于不同生物相容性固体表面的润湿能力。此外,密度,张力表面,并测量室温下溶液的粘度。结果表明,由于内聚力和粘附力的不同分布,在血液中引入尺寸分布集中在约 50 nm 的金纳米颗粒通常会提高润湿能力并改变溶液的其他特性。
更新日期:2018-06-12
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