Potato common scab caused by bacterial pathogen Streptomyces scabies (Thaxt.) Waksman & Henrici is one of the most important diseases of potato ( Solanum tuberosum L.) worldwide. Currently, the most effective and desirable method to control common scab is through the use of resistant cultivars. In order to decipher the genetic control of resistance to common scab disease in Canadian potato germplasm, an association panel of 143 clones including advanced breeding clones and commercial cultivars was genotyped with 12K SolCAP SNPs and phenotyped for potato common scab resistances in multiple years. By conducting a genome-wide association analysis (GWAS) using GWASpoly R package, three resistance QTLs were identified on potato chromosomes 2, 4, and 12, respectively. The phenotypic variation explained by these QTLs was 21%, 19%, and 26%, respectively. The QTL on chromosome 2 was simplex-dominant whereas duplex-dominant QTLs were identified on chromosomes 4 and 12. These findings will be useful to design marker-assisted selection and breeding strategies to improve resistance to common scab in new potato cultivars.

中文翻译：

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马铃薯赤霉病抗性的全基因组关联研究

由细菌性病原体链霉菌疥疮（Thaxt.）Waksman & Henrici 引起的马铃薯常见疮痂病是世界范围内马铃薯（Solanum tuberosum L.）最重要的病害之一。目前，控制常见疮痂病的最有效和最理想的方法是使用抗病品种。为了破译加拿大马铃薯种质中对常见疮痂病抗性的遗传控制，对包括高级育种克隆和商业栽培品种在内的 143 个克隆进行了基因分型，并用 12K SolCAP SNP 进行了多年的马铃薯常见疮痂病抗性表型分析。通过使用 GWASpoly R 包进行全基因组关联分析 (GWAS)，分别在马铃薯染色体 2、4 和 12 上鉴定了三个抗性 QTL。这些 QTL 解释的表型变异为 21%、19% 和 26%，分别。2 号染色体上的 QTL 是单链显性，而双链显性 QTL 在 4 号和 12 号染色体上被鉴定。这些发现将有助于设计标记辅助选择和育种策略，以提高马铃薯新品种对常见疮痂病的抗性。