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Effect of Aortic Wall Deformation with Healthy and Calcified Annulus on Hemodynamic Performance of Implanted On-X Valve.
Cardiovascular Engineering and Technology ( IF 1.8 ) Pub Date : 2020-01-07 , DOI: 10.1007/s13239-019-00453-y Masod Sadipour 1 , Pedram Hanafizadeh 1 , Keyvan Sadeghy 1 , Amirmohammad Sattari 1
中文翻译:
健康且钙化环带对主动脉壁的变形对植入式On-X瓣膜血流动力学性能的影响。
更新日期:2020-01-07
Cardiovascular Engineering and Technology ( IF 1.8 ) Pub Date : 2020-01-07 , DOI: 10.1007/s13239-019-00453-y Masod Sadipour 1 , Pedram Hanafizadeh 1 , Keyvan Sadeghy 1 , Amirmohammad Sattari 1
Affiliation
Introduction
In this research, the hemodynamic performance of a 23-mm On-X bileaflet mechanical heart valve (BMHV) was investigated with the realistic geometry model of the valve and the deformable aorta in accelerating systole. In addition, the effect of ascending aorta flexibility and aortic annulus calcification on the complex blood flow characteristics were investigated.Methods
The geometry of the aorta is derived from the medical images, and the Ogden model has been utilized for the mechanical behavior of the ascending aorta. The 3D numerical simulation by a two-way Fluid-Structure Interaction (FSI) analysis using the Arbitrary Lagrangian–Eulerian (ALE) method was performed throughout the accelerating systolic phase.Results
The dynamics of the leaflets are investigated, and blood flow characteristics such as velocities, vorticities as well as viscous and turbulent shear stress were precisely captured in the flow domain specifically in the hinge region. Streamline results are in accordance with the previously reported data, which show that the flared On-X valves inlet yields a more uniform flow in accelerating systole. Simulations show that aorta flexibility or valve annulus calcification causes variations up to 7% in maximum fluid velocity and 20% in Turbulence Kinetic Energy (TKE).Conclusions
In this study, the complex flow field characteristics in the new generation of BMHVs considering aorta flexibility with healthy and calcified annulus were investigated. It was found that the blood flow around the hinges region is in the danger of hemolysis and platelet activation and subsequently thromboembolism. Furthermore, the results show that similar to vessel wall deformation, considering the probable annulus calcification after valve replacement is also essential.中文翻译:
健康且钙化环带对主动脉壁的变形对植入式On-X瓣膜血流动力学性能的影响。