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Bloodstream Infection of a Cancer Patient by Cystobasidium minutum: A Case Report and Literature Review
Mycopathologia ( IF 5.5 ) Pub Date : 2020-01-02 , DOI: 10.1007/s11046-019-00415-x
Cicero P Inácio 1, 2 , Madi V Diniz 2 , Paulo Sergio R Araújo 3, 4 , Marilane S Barros 4 , Melyna C L Andrade 1 , Reginaldo G Lima-Neto 1 , Danielle Patrícia C Macêdo 5 , Rejane P Neves 2
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Emergent fungal infections are uncommon conditions which frequently lead to death. To our knowledge, only a few cases of invasive infection by Cystobasidium minutum (previously known as Rhodotorula minuta) have been reported. Moreover, several factors are responsible for deep site infections, such as catheter-related fungemia. This report describes the first case report of Cystobasidium minutum causing fungemia in Brazil. The pathogens fungemia was demonstrated by catheter and blood culture-proven, and both yeasts were identified by sequences of D1/D2 rDNA region. After the end of antifungal therapy and catheter removal, a second blood culture was found to be negative and the clinical signs and symptoms of the patient improved.

中文翻译:

微小囊孢子菌对癌症患者的血流感染:病例报告及文献复习

紧急真菌感染是不常见的情况,经常导致死亡。据我们所知,只有少数小孢子菌(以前称为小红酵母)侵入性感染的报道。此外,有几个因素会导致深部感染,例如导管相关的真菌血症。本报告描述了巴西第一例微小囊孢子菌引起真菌血症的病例报告。病原体真菌血症经导管和血液培养证实,两种酵母菌均通过D1/D2 rDNA区序列鉴定。抗真菌治疗结束并拔除导管后,第二次血培养呈阴性,患者的临床体征和症状有所改善。
更新日期:2020-01-02
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