At present, many kinds of materials are used for bone tissue engineering, such as polymer materials, metals, etc., which in general have good biocompatibility and mechanical properties. However, these materials cannot be controlled artificially after implantation, which may result in poor repair performance. The appearance of the magnetic response material enables the scaffolds to have the corresponding ability to the external magnetic field. Within the magnetic field, the magnetic response material can achieve the targeted release of the drug, improve the performance of the scaffold, and further have a positive impact on bone formation. This paper first reviewed the preparation methods of magnetic responsive materials such as magnetic nanoparticles, magnetic polymers, magnetic bioceramic materials and magnetic alloys in recent years, and then introduced its main applications in the field of bone tissue engineering, including promoting osteogenic differentiation, targets release, bioimaging, cell patterning, etc. Finally, the mechanism of magnetic response materials to promote bone regeneration was introduced. The combination of magnetic field treatment methods will bring significant progress to regenerative medicine and help to improve the treatment of bone defects and promote bone tissue repair.

目前，用于骨组织工程的多种材料，例如聚合物材料，金属等，通常具有良好的生物相容性和机械性能。然而，这些材料在植入后不能被人为控制，这可能导致较差的修复性能。磁响应材料的出现使支架具有对外部磁场的相应能力。在磁场内，磁响应材料可以实现药物的靶向释放，改善支架的性能，并进一步对骨骼形成产生积极影响。本文首先综述了近年来磁性响应材料的制备方法，例如磁性纳米颗粒，磁性聚合物，磁性生物陶瓷材料和磁性合金。然后介绍了其在骨组织工程领域的主要应用，包括促进成骨细胞分化，靶标释放，生物成像，细胞图案形成等。最后，介绍了磁响应材料促进骨再生的机理。磁场治疗方法的结合将为再生医学带来重大进展，并有助于改善骨缺损的治疗并促进骨组织修复。