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Silk: A Promising Biomaterial Opening New Vistas Towards Affordable Healthcare Solutions
Journal of the Indian Institute of Science ( IF 2.3 ) Pub Date : 2019-08-24 , DOI: 10.1007/s41745-019-00114-y
Ashutosh Bandyopadhyay , Suvro Kanti Chowdhury , Souradeep Dey , Joseph Christakiran Moses , Biman B. Mandal

Substantial progress in biomaterial research over the years has culminated in revolutionary technological advancements in the healthcare domain. This has triggered the quest for affordable healthcare solutions with focus on sustainable biomaterials with versatile applications endowed with green fabrication strategies. Silk as a biopolymer has garnered special attention which can largely be attributed to the excellent material properties of silk in addition to its affordability and resource ability. Silk fibroin from various silkworm and spider species and sericin from various silkworm species have been researched for their potential applications in the healthcare industry such as tissue-engineered grafts, cancer therapeutics, high-throughput tissue-on-chip models, food preservatives, biomedical imaging, biosensing, biomedical textiles, implants, cosmetics and bioremediation products. The present review mainly focusses on the various sources of silk fibroin and its relevant properties that have been conferred to it by nature. Moreover, recent developments, progress and prevalent modalities of healthcare industry that involve the application of silk fibroin and sericin have been outlined in the present review.

中文翻译:

Silk:一种有前途的生物材料,为经济实惠的医疗保健解决方案开辟了新的前景

多年来,生物材料研究取得了重大进展,最终在医疗保健领域实现了革命性的技术进步。这引发了对负担得起的医疗保健解决方案的追求,重点是具有绿色制造策略的多功能应用的可持续生物材料。丝绸作为一种生物聚合物受到了特别的关注,这在很大程度上归功于丝绸的优异材料特性,以及其可负担性和资源能力。研究了来自各种蚕和蜘蛛物种的丝素蛋白以及来自各种蚕种的丝胶在医疗保健行业的潜在应用,如组织工程移植、癌症治疗、高通量芯片模型、食品防腐剂、生物医学成像、生物传感、生物医学纺织品、植入物、化妆品和生物修复产品。本综述主要关注丝素蛋白的各种来源及其自然赋予的相关特性。此外,本综述还概述了涉及丝素蛋白和丝胶应用的医疗保健行业的最新发展、进展和流行方式。
更新日期:2019-08-24
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