When planning a fluorine labeling strategy for ¹⁹F solid state NMR (ssNMR) studies of the structure and/or mobility of fluorine labeled compounds in situ in an oriented biological system, it is important to characterize the NMR properties of the label. This manuscript focuses on the characterization of a selection of aromatic fluorine compounds in dimyristoylphosphatidylcholine bilayers using ¹⁹F ssNMR from the standpoint of determining the optimum arrangement of fluorine nuclei on a pendant aromatic ring before incorporation into more complex biological systems.

中文翻译：

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优化定向生物系统中19 F固态NMR的氟标记

当计划在定向生物系统中原位进行氟标记化合物的结构和/或迁移率的¹⁹ F固态NMR（ssNMR）研究的氟标记策略时，表征标记的NMR特性非常重要。从确定掺入更复杂的生物系统之前，确定氟核在侧链芳环上的最佳排列的角度出发，该手稿着重于使用¹⁹ F ssNMR表征二豆蔻酰基磷脂酰胆碱双分子层中精选的芳族氟化合物。