当前位置: X-MOL 学术Cardiovasc. Eng. Technol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A Systematic Review for the Design of In Vitro Flow Studies of the Carotid Artery Bifurcation.
Cardiovascular Engineering and Technology ( IF 1.8 ) Pub Date : 2019-12-10 , DOI: 10.1007/s13239-019-00448-9
A M Hoving 1 , E E de Vries 2 , J Mikhal 1 , G J de Borst 2 , C H Slump 1
Affiliation  

Purpose

In vitro blood flow studies in carotid artery bifurcation models may contribute to understanding the influence of hemodynamics on carotid artery disease. However, the design of in vitro blood flow studies involves many steps and selection of imaging techniques, model materials, model design, and flow visualization parameters. Therefore, an overview of the possibilities and guidance for the design process is beneficial for researchers with less experience in flow studies.

Methods

A systematic search to in vitro flow studies in carotid artery bifurcation models aiming at quantification and detailed flow visualization of blood flow dynamics results in inclusion of 42 articles.

Results

Four categories of imaging techniques are distinguished: MRI, optical particle image velocimetry (PIV), ultrasound and miscellaneous techniques. Parameters for flow visualization are categorized into velocity, flow, shear-related, turbulent/disordered flow and other parameters. Model materials and design characteristics vary between study type.

Conclusions

A simplified three-step design process is proposed for better fitting and adequate match with the pertinent research question at hand and as guidance for less experienced flow study researchers. The three consecutive selection steps are: flow parameters, image modality, and model materials and designs. Model materials depend on the chosen imaging technique, whereas choice of flow parameters is independent from imaging technique and is therefore only determined by the goal of the study.


中文翻译:

颈动脉分叉体外血流研究设计的系统综述。

目的

颈动脉分叉模型中进行体外血流研究可能有助于理解血液动力学对颈动脉疾病的影响。但是,体外血流研究的设计涉及许多步骤以及成像技术,模型材料,模型设计和血流可视化参数的选择。因此,对于流程研究经验较少的研究人员,对设计过程的可能性和指导进行概述是有益的。

方法

系统地搜索颈动脉分叉模型中的体外血流研究,旨在量化和详细显示血流动力学的血流,结果包括42篇文章。

结果

成像技术分为四类:MRI,光学粒子图像测速(PIV),超声和其他技术。用于流量可视化的参数分为速度,流量,与剪切有关的,湍流/无序流量和其他参数。模型材料和设计特征因研究类型而异。

结论

提出了简化的三步设计过程,以更好地拟合和充分匹配当前的相关研究问题,并为经验不足的流量研究人员提供指导。三个连续的选择步骤是:流量参数,图像模态以及模型材料和设计。模型材料取决于所选的成像技术,而流量参数的选择与成像技术无关,因此只能由研究目的确定。
更新日期:2019-12-10
down
wechat
bug