Cochlear implants are one of the most successful neuroprosthetic devices that have been developed to date. Profoundly deaf patients can achieve speech perception after complete loss of sensory input. Despite the improvements many patients experience, there is still a large degree of outcome variability. It has been proposed that central plasticity may be a major factor in the different levels of benefit that patients experience. However, the neural mechanisms of how plasticity impacts cochlear implant learning and the degree of plasticity's influence remain unknown. Here, we review the human and animal research on three of the main ways that central plasticity affects cochlear implant outcomes.

中文翻译：

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人工耳蜗使用者的听觉皮质可塑性。

耳蜗植入物是迄今为止开发的最成功的神经修复装置之一。完全聋的患者在感觉输入完全丧失后可以实现语音感知。尽管许多患者经历了改善，但结果差异仍然很大。已经提出，中央可塑性可能是患者体验到的不同收益水平的主要因素。然而，可塑性如何影响人工耳蜗学习和可塑性影响程度的神经机制仍然未知。在这里，我们回顾了中心可塑性影响人工耳蜗植入结果的三种主要方式的人类和动物研究。