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An Approach to Parallel Algorithms for Long DNA Sequences Alignment on Manycore Architecture.
Journal of Computational Biology ( IF 1.7 ) Pub Date : 2020-08-04 , DOI: 10.1089/cmb.2019.0362
Evaldo Bezerra Costa 1 , Gabriel Pereira Silva 1 , Marcello Goulart Teixeira 1
Affiliation  

The DNA sequencing process has evolved rapidly due to the development of new technologies and equipment capable of producing large amounts of sequencing data. Among these methods, PacBio stands out. The PacBio method uses single molecule real-time, generating sequence files composed by long reads. Storage and analysis of the data generated became a challenge ushering in the development of bioinformatic tools. One of these challenges is the alignment of these sequences. This article describes techniques and processes developed for long DNA sequence alignment using manycore architecture.

中文翻译:

多核架构上长 DNA 序列比对的并行算法方法。

由于能够产生大量测序数据的新技术和设备的发展,DNA 测序过程发展迅速。在这些方法中,PacBio 脱颖而出。PacBio 方法使用单分子实时,生成由长读取组成的序列文件。生成的数据的存储和分析成为引领生物信息学工具发展的挑战。这些挑战之一是这些序列的比对。本文描述了使用多核架构为长 DNA 序列比对开发的技术和过程。
更新日期:2020-08-08
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