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Phytoconstituents of Adenanthera pavonina Linn from the bark extracts
Beni-Suef University Journal of Basic and Applied Sciences Pub Date : 2019-12-01 , DOI: 10.1186/s43088-019-0013-0
Arzumand Ara , Md. Moshfekus Saleh-E-In , Md. Abul Hashem , Mesbahuddin Ahmad , Choudhury Mahmood Hasan

Adenanthera pavonina L. is an important medicinal plant and its barks are used in traditional medicine for treating different diseases. Therefore, a phytochemical investigation was carried out to isolate and identify secondary metabolites from its barks. Seven compounds namely ethyl 3,3-dimethyl-13-hydroxytridecanoate (1), stigmasta-5,22-dien-3β-ol (2), tert.butyl tridecanoate (3), 6-α-hydroxy stigmast-20(21)-en-3-one (4) of dichloromethane extract and 18-(2′, 3′-dihydroxyphenyl)nonadec-17-en-2-ol (5), 1-(N-propyl amino)-2-henecosanone (6), and stigmast–5(6), 20(21)-diene-3-one (7) were isolated from the barks of Adenanthera pavonina Linn. Of these compounds, 1, 4, 5, 6, and 7 appear new. The structures of these compounds were elucidated by spectroscopic techniques, mainly by NMR. Five new and two known compounds have been isolated and characterized from the bark of A. pavonina. The isolated compounds could be a potential template for the synthesis and development of new lead compounds with interesting pharmacological properties.

中文翻译:

来自树皮提取物的 Adenanthera pavonina Linn 的植物成分

Adenanthera pavonina L. 是一种重要的药用植物,其树皮在传统医学中用于治疗不同的疾病。因此,进行了植物化学研究以从其树皮中分离和鉴定次生代谢物。七种化合物即3,3-二甲基-13-羟基十三酸乙酯(1)、stigmasta-5,22-dien-3β-ol(2)、十三酸叔丁酯(3)、6-α-羟基stigmast-20(21) )-en-3-one (4) 二氯甲烷提取物和 18-(2', 3'-dihydroxyphenyl)nonadec-17-en-2-ol (5), 1-(N-丙基氨基)-2-henecosanone (6) 和 stigmast–5(6), 20(21)-diene-3-one (7) 从 Adenanthera pavonina Linn 的树皮中分离出来。在这些化合物中,1、4、5、6 和 7 看起来是新的。这些化合物的结构通过光谱技术,主要是通过核磁共振来阐明。已从 A. pavonina 的树皮中分离并表征了五种新化合物和两种已知化合物。分离的化合物可能是合成和开发具有有趣药理特性的新先导化合物的潜在模板。
更新日期:2019-12-01
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