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From electric circuits to chemical networks
Natural Computing ( IF 2.1 ) Pub Date : 2019-09-16 , DOI: 10.1007/s11047-019-09761-7
Luca Cardelli , Mirco Tribastone , Max Tschaikowski

Electric circuits manipulate electric charge and magnetic flux via a small set of discrete components to implement useful functionality over continuous time-varying signals represented by currents and voltages. Much of the same functionality is useful to biological organisms, where it is implemented by a completely different set of discrete components (typically proteins) and signal representations (typically via concentrations). We describe how to take a linear electric circuit and systematically convert it to a chemical reaction network of the same functionality, as a dynamical system. Both the structure and the components of the electric circuit are dissolved in the process, but the resulting chemical network is intelligible. This approach provides access to a large library of well-studied devices, from analog electronics, whose chemical network realization can be compared to natural biochemical networks, or used to engineer synthetic biochemical networks.

中文翻译:

从电路到化学网络

电路通过一小组离散组件操纵电荷和磁通量,以在由电流和电压表示的连续时变信号上实现有用的功能。许多相同的功能对于生物体有用,在生物体中,它是由一组完全不同的离散成分(通常是蛋白质)和信号表示(通常是通过浓度)实现的。我们描述了如何采用线性电路并将其系统地转换为具有相同功能的化学反应网络,作为动力系统。电路的结构和组件都在此过程中被溶解,但是生成的化学网络是可理解的。通过这种方法,您可以从模拟电子设备访问经过广泛研究的设备库,
更新日期:2019-09-16
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