This article demonstrates a scalable, time-division multiplexed biopotential recording front-end capable of real-time differential- and common-mode artifact suppression. A delta-encoded recording architecture exploits the power spectral density (PSD) characteristics of Electrocorticography (ECoG) recordings, combining an 8-bit ADC, and an 8-bit DAC to achieve 14 bits of dynamic range. The flexibility of the digital feedback architecture is leveraged to time-division multiplex 64 differential input channels onto a shared mixed-signal front-end, reducing channel area by 2x compared to the state-of-the-art. The feedback DAC used for delta-encoding also serves to cancel differential artifacts with an off-chip adaptive loop. Analysis of this architecture and measured silicon performance of a 65 nm CMOS test-chip implementation, both on the bench and in-vivo, are included with this paper.

中文翻译：

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A 0.0023 毫米 2/通道。具有刺激伪影抑制功能的 Delta 编码、时分复用混合信号 ECoG 记录架构。

本文演示了一个可扩展的时分复用生物电势记录前端，能够实时抑制差分和共模伪影。增量编码记录架构利用皮层脑电图 (ECoG) 记录的功率谱密度 (PSD) 特性，结合 8 位 ADC 和 8 位 DAC 来实现 14 位动态范围。利用数字反馈架构的灵活性，将 64 个差分输入通道时分复用到一个共享的混合信号前端，与最先进的技术相比，通道面积减少了 2 倍。用于增量编码的反馈 DAC 还用于通过片外自适应环路消除差分伪影。分析此架构并测量 65 nm CMOS 测试芯片实现的硅性能，