Recurrent depressive episodes during adolescence result in significant impairment and increased risk for subsequent adverse outcomes throughout the life span. Evidence suggests that early pubertal timing predicts the onset of depressive episodes (particularly for girls); however, it is not known if pubertal timing prospectively predicts recurrent depressive episodes in youth.

中文翻译：

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青春期提前预测男孩和女孩抑郁发作的发作和复发。

青春期反复发作的抑郁会导致严重的损害，并增加整个生命周期中后续不良后果的风险。有证据表明，青春期提前可以预测抑郁发作（尤其是女孩）；然而，尚不清楚青春期时间是否能前瞻性地预测青年抑郁症的反复发作。