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Aspalathin Protects Insulin-Producing β Cells against Glucotoxicity and Oxidative Stress-Induced Cell Death.
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2020-02-12 , DOI: 10.1002/mnfr.201901009
Céline Moens 1 , Mohammed Bensellam 2 , Eddy Himpe 1 , Christo J F Muller 3 , Jean-Christophe Jonas 2 , Luc Bouwens 1
Affiliation  

Aspalathin, the main polyphenolic phytochemical of rooibos (Aspalathus linearis), has been attributed with health promoting properties, including a glucose lowering effect that can prove interesting for application as nutraceutical or therapeutic in (pre‐)diabetics. Preservation of β cell mass in the pancreas is considered a key issue for diabetes prevention or treatment, therefore the aim is to investigate whether aspalathin also has β cell cytoprotective potential.

中文翻译:

Aspalathin保护产生胰岛素的β细胞免受糖毒性和氧化应激诱导的细胞死亡。

芦荟(Aspalathus linearis)的主要多酚植物化学物质Aspalathin具有促进健康的特性,包括降低血糖的作用,在(糖尿病前期)糖尿病患者中作为营养保健品或治疗剂很有用。胰腺中β细胞团的保存被认为是糖尿病预防或治疗的关键问题,因此目的是研究阿斯帕拉丁是否也具有β细胞的细胞保护潜力。
更新日期:2020-02-12
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