In the present study, a cauliflower‐like NiCo₂O₄−Zn/Al layered double hydroxide (NiCo₂O₄−Zn/Al LDH) nanocomposite was used as a novel electrode material for the sensitive and selective determination of pyridoxine (vitamin B₆). The structure and morphology of the as‐prepared nanocomposite were characterized by X‐ray diffraction (XRD), FT‐IR, field emission scanning electron microscopy (FESEM) and energy dispersive X‐ray spectroscopy (EDX). The NiCo₂O₄−Zn/Al LDH nanocomposite exhibited excellent electrocatalytic ability in the oxidation of pyridoxine, which could result from the synergistic effect of the two components. The developed sensor also provided a selective determination of pyridoxine in the presence of other species such as vitamins (B₁, B₂, B₁₂ and ascorbic acid), inorganic ions and biomolecules. The fabricated sensor showed a good linear response for pyridoxine over the concentration ranges 2×10⁻⁷–2.0×10⁻⁴ mol L⁻¹ with a low detection limit of 8.6×10⁻⁸ mol L⁻¹. Finally, the proposed method was successfully applied for the determination of pyridoxine in commercial tablets and plasma samples with satisfactory results. Furthermore, this novel sensor displayed superior benefits in terms of stability, sensitivity, repeatability and cost. The present work aims to expand NiCo₂O₄ based nanocomposites to sensor fields and promote the development of pyridoxine sensors.

中文翻译：

---

花椰菜状NiCo2O4-Zn / Al层状双氢氧化物纳米复合材料，作为选择性吡y醇检测的高效电化学传感平台

在本研究中，使用花椰菜状NiCo ₂ O ₄ -Zn / Al层状双氢氧化物（NiCo ₂ O ₄ -Zn / Al LDH）纳米复合材料作为新型电极材料，用于灵敏和选择性测定吡ido醇（维生素B ₆）。制备的纳米复合材料的结构和形貌通过X射线衍射（XRD），傅立叶变换红外（FT-IR），场发射扫描电子显微镜（FESEM）和能量色散X射线光谱（EDX）进行表征。NiCo ₂ O ₄-Zn / Al LDH纳米复合材料在吡ido醇的氧化中表现出优异的电催化能力，这可能是由于两种成分的协同作用所致。开发的传感器还可以在维生素（B ₁，B ₂，B ₁₂和抗坏血酸），无机离子和生物分子等其他物种存在下选择性测定吡ido醇。所制造的传感器在2×10 ^-7 –2.0×10 ^-4  mol L ^-1的浓度范围内对吡ido醇表现出良好的线性响应，检测限低至8.6×10 ^-8  mol L ^-1。最终，该方法成功用于商业片剂和血浆样品中吡ido醇的测定，结果令人满意。此外，这种新型传感器在稳定性，灵敏性，可重复性和成本方面显示出卓越的优势。本工作旨在将基于NiCo ₂ O ₄的纳米复合材料扩展到传感器领域，并促进吡ido醇传感器的发展。