Understanding, predicting, and controlling the self-assembly behavior of stimuli-responsive block copolymers remains a pertinent challenge. As such, the copolymer blending protocol provides an accessible methodology for obtaining a range of intermediate polymeric nanostructures simply by blending two or more block copolymers in the desired molar ratio to target specific stimuli-responsiveness. Herein, thermoresponsive diblock copolymers are blended in various combinations to investigate whether the resultant cloud point temperature can be modulated by simple manipulation of the molar ratio. Thermoresponsive amphiphilic diblock copolymers composed of statistical poly(n-butyl acrylate-co-N,N-dimethylacrylamide) core-forming blocks and four different thermoresponsive corona-forming blocks, namely poly(diethylene glycol monomethyl ether methacrylate) (p(DEGMA)), poly(N-isopropylacrylamide), poly(N,N-diethylacrylamide), and poly(oligo(ethylene glycol) monomethyl ether methacrylate) (p(OEGMA)) are selected for evaluation. Using variable temperature turbidimetry, the thermoresponsive behavior of blended diblock copolymer self-assemblies is assessed and compared to the thermoresponsive behavior of the constituent pure diblock copolymer micelles to determine whether comicellization is achieved and more significantly, whether the two blended corona-forming thermoresponsive blocks exhibit cooperative behavior. Interestingly, blended diblock copolymer micelles composed of p(DEGMA)/p(OEGMA) mixed coronae display cooperative behavior, highlighting the potential of copolymer blending for the preparation of stimuli-responsive nanomaterials in applications such as oil recovery, drug delivery, biosensing, and catalysis.

中文翻译：

---

聚合物共混中合作性的重要性：控制共混嵌段共聚物胶束的热响应行为。

理解，预测和控制刺激响应性嵌段共聚物的自组装行为仍然是一个挑战。这样，共聚物共混方案为简单地通过以期望的摩尔比共混两种或更多种嵌段共聚物以靶向特定的刺激响应性而获得一系列中间聚合物纳米结构提供了可及的方法。在此，以各种组合共混热敏性二嵌段共聚物以研究是否可以通过简单地控制摩尔比来调节所得的浊点温度。由统计型聚丙烯酸正丁酯-co-N，N-二甲基丙烯酰胺核形成嵌段和四种不同的热电晕形成嵌段组成的热敏性两亲二嵌段共聚物，即聚（二甘醇单甲基醚甲基丙烯酸酯）（p（DEGMA）），聚（N-异丙基丙烯酰胺），聚（N，N-二乙基丙烯酰胺）和聚（低聚乙二醇单甲基醚甲基丙烯酸酯）（p（OEGMA））选择进行评估。使用可变温度比浊法，评估了共混二嵌段共聚物自组装体的热响应行为，并将其与纯二嵌段共聚物胶束的热响应行为进行了比较，以确定是否实现了漫画化，更重要的是，这两种共混的形成电晕的热敏嵌段是否表现出合作行为。有趣的是，由p（DEGMA）/ p（OEGMA）混合电晕组成的共混二嵌段共聚物胶束表现出协同行为，