当前位置: X-MOL 学术J. Cachexia Sarcopenia Muscle › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A counterintuitive perspective for the role of fat-free mass in metabolic health.
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2020-01-30 , DOI: 10.1002/jcsm.12520
Jean-Christophe Lagacé 1, 2 , Martin Brochu 1, 2 , Isabelle J Dionne 1, 2
Affiliation  

Fat-free mass (FFM) has long been recognized to play a role in metabolic homeostasis. Over the years, it has become widely accepted by the scientific and general community alike that having a greater FFM can be protective for metabolic health. Hence, in the context of an aging population concurrently facing sarcopenia and an elevated incidence of metabolic diseases, substantial efforts are being made to study and develop interventions aiming to maintain or increase FFM. However, accumulating evidence now suggests that a large FFM may be deleterious to metabolic health, at least in some populations. The objective of this article is thus to raise awareness surrounding these results and to explore possible explanations and mechanisms underlying this counterintuitive association.

中文翻译:

无脂肪物质在代谢健康中的作用有悖常理。

长期以来,无脂脂肪(FFM)在代谢稳态中起着重要作用。多年来,科学和公众都广泛接受具有较高的FFM可以保护代谢健康。因此,在人口老龄化的同时面对肌肉减少症和代谢疾病发生率升高的情况下,人们正在作出大量努力来研究和开发旨在维持或增加FFM的干预措施。但是,现在越来越多的证据表明,至少在某些人群中,大量的FFM可能对代谢健康有害。因此,本文的目的是提高人们对这些结果的认识,并探索这种违反直觉的关联的可能解释和机制。
更新日期:2020-01-30
down
wechat
bug