Erectile dysfunction (ED) is a common disorder among men, with significant public health implications. Current therapies have certain limitations including efficacy and safety issues, necessitating the development of novel therapeutic strategies for ED. Nanotechnology-based drug delivery systems are being explored to overcome these limitations with promising in vitro and in vivo efficacies. In particular, lipid-based nanoparticles have generated considerable interest owing to their potential to enhance drug bioavailability, and decrease side effects and drug susceptibility to metabolism. This review summarizes the recent findings using lipid-based nanoparticles in ED therapy.

中文翻译：

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基于脂质的纳米颗粒治疗勃起功能障碍。

勃起功能障碍（ED）是男性常见的疾病，对公共健康有重大影响。当前的疗法具有一定的局限性，包括功效和安全性问题，因此有必要开发新的ED治疗策略。人们正在探索基于纳米技术的药物递送系统，以克服这些局限性，并有望实现体外和体内功效。特别地，基于脂质的纳米颗粒由于其具有增强药物生物利用度，减少副作用和药物对代谢的敏感性的潜力而引起了极大的兴趣。这篇综述总结了在ED疗法中使用基于脂质的纳米颗粒的最新发现。