BACKGROUND Combined spinal-epidural anesthesia (CSEA) can be performed with either a single-space technique or a double-space technique for cesarean section. We performed a double-blind randomized controlled study to compare the effect of the double-space technique with that of the single-space technique on sensory block level and side effects. METHODS Parturients undergoing elective cesarean section under regional anesthesia were randomized to receive CSEA with either the double-space technique (double group, n = 20) or the single-space technique (single group, n = 20). In the double group, an epidural catheter was inserted at the L1-2 interspace, and dural puncture was performed at the L3-4 interspace. In the single group, the procedure was performed at the L3-4 interspace using the needle-through-needle technique. RESULTS There were no differences in time to readiness or intraoperative level of sensory block between the two groups. The postoperative sensory level was maintained at a higher level in the double group than in the single group (1 h postoperatively, P = 0.029; 6 h postoperatively, P = 0.016). There was no difference between the two groups in terms of side effects. The parturient satisfaction scores 48 h postoperatively were significantly different between groups (9.5 in the double group vs. 8 in the single group, P = 0.004). CONCLUSIONS We conclude that there were no differences in intraoperative variables between the double-space technique and the single-space technique for CSEA. However, double-space CSEA for cesarean section may be beneficial for controlling postoperative pain and improving parturient satisfaction. TRIAL REGISTRATION The study was retrospectively registered at https://cris.nih.go.kr under the trial ID KCT0002514. Date of registration: October 27, 2017.

中文翻译：

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剖宫产脊髓硬膜外联合麻醉中双空间技术与单空间技术的随机双盲比较。

背景技术可以使用单空间技术或双空间技术对剖宫产术进行脊柱-硬膜外联合麻醉（CSEA）。我们进行了一项双盲随机对照研究，以比较双空间技术和单空间技术对感觉阻滞水平和副作用的影响。方法采用双空间技术（双组，n = 20）或单空间技术（单组，n = 20）将接受区域麻醉的剖宫产产妇随机接受CSEA。在两组中，在L1-2间隙插入硬膜外导管，在L3-4间隙进行硬膜穿刺。在单个组中，使用穿刺针技术在L3-4间隙进行手术。结果两组在准备时间或术中感觉阻滞水平上没有差异。两组的术后感觉水平均维持在较高水平（术后1 h，P = 0.029；术后6 h，P = 0.016）。两组在副作用方面没有差异。术后48 h的产妇满意度得分在两组之间有显着差异（双组为9.5，单组为8，P = 0.004）。结论我们得出结论，CSEA的双空间技术和单空间技术在术中变​​量方面没有差异。但是，剖宫产的双空间CSEA可能有助于控制术后疼痛和提高产妇满意度。试验注册该研究已通过https://cris.nih.go.kr进行了追溯注册，注册号为KCT0002514。注册日期：2017年10月27日。