Peripheral artery disease is an atherosclerotic disease of the lower extremities associated with high cardiovascular mortality. Management of this condition may include lifestyle modifications, medical management, endovascular repair, or surgery. The medical approach to peripheral artery disease is multifaceted and includes cholesterol reduction, antiplatelet therapy, anticoagulation, peripheral vasodilators, blood pressure management, exercise therapy, and smoking cessation. Adherence to this regimen can reduce limb-related complications like critical limb ischemia and amputation, as well as systemic complications of atherosclerosis like stroke and myocardial infarction. Relative to coronary artery disease, peripheral artery disease is an undertreated condition. In this article, we explore the evidence behind medical therapies for the management of peripheral artery disease.

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循证医学对周围动脉疾病的管理。

周围动脉疾病是下肢的动脉粥样硬化疾病，伴有较高的心血管死亡率。这种状况的管理可能包括生活方式的改变，医疗管理，血管内修复或手术。外周动脉疾病的医学方法是多方面的，包括降低胆固醇，抗血小板治疗，抗凝，外周血管扩张剂，血压管理，运动疗法和戒烟。坚持该方案可以减少与肢体相关的并发症，例如严重的肢体缺血和截肢，以及动脉粥样硬化的全身性并发症，例如中风和心肌梗塞。相对于冠状动脉疾病，外周动脉疾病是一种治疗不足的疾病。在这篇文章中，