Epigenetic alterations have been associated with a wide range of diseases. Furthermore, many therapeutic interventions modelling environmental exposures appear to involve epigenetic mechanisms. Recent progress has been made in developing drugs targeting specific epigenetic components. Here, I propose developing 'epimimetics', novel drugs that mimic or enhance therapeutic effects of epigenetic modifications.

中文翻译：

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Epimimetics：针对表观遗传介体和调节剂的新型疗法。

表观遗传改变与多种疾病有关。此外，许多模拟环境暴露的治疗性干预似乎都涉及表观遗传机制。在开发靶向特定表观遗传成分的药物方面取得了最新进展。在这里，我提议开发“模仿剂”，一种模仿或增强表观遗传修饰的治疗作用的新型药物。