Private companies have recently started to sell epigenetic tests to the public online, most of them without supervision by a physician. While the ethical and legal implications of direct-to-consumer genetic testing have received considerable attention over the past decades, other direct-to-consumer ‘omic’ tests have largely escaped scrutiny. Direct-to-consumer epigenetic tests have the potential to reveal sensitive information about individuals, such as disease risk and exposure history. Yet regulation lags behind purely genetics-based tests. In this Comment article, the authors discuss the salient ethical and legal considerations of direct-to-consumer epigenetic tests.

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出售直接面向消费者的表观遗传测试：我们准备好了吗？

私人公司最近开始在网上向公众出售表观遗传测试，其中大多数未经医生监督。尽管在过去的几十年中，直接面向消费者的基因测试在伦理和法律方面受到了广泛关注，但其他直接面向消费者的“组学”测试在很大程度上没有受到审查。直接面向消费者的表观遗传测试有可能揭示有关个人的敏感信息，例如疾病风险和接触史。然而，监管落后于纯粹基于遗传学的测试。在这篇评论文章中，作者讨论了直接面向消费者的表观遗传测试的重要伦理和法律考虑。