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The Effect of Lactobacillus fermentum ME-3 Treatment on Glycation and Diabetes Complications.
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2020-02-17 , DOI: 10.1002/mnfr.201901018
Axel Guilbaud 1, 2, 3 , Michael Howsam 1, 3 , Céline Niquet-Léridon 3, 4 , Florian Delguste 1 , Marc Fremont 2 , Sophie Lestavel 5 , Patrice Maboudou 6 , Anne Garat 7 , Susanna Schraen 6 , Brigitte Onraed 6 , Benoît Foligné 8 , Éric Boulanger 1, 3 , Frédéric J Tessier 1, 3
Affiliation  

Type 2 diabetes (T2D) induces organ damage associated with glycation, among other metabolic pathways. While therapeutic strategies have been tested to reduce the formation and impact of glycation products, results remain equivocal. Anti‐diabetic therapies using probiotics have been proposed, but their effect upon glycation has not been reported. Here, the effects of the bacterial strain Lactobacillus fermentum ME‐3 on glycation and T2D‐related complications in a mouse model of T2D are investigated.

中文翻译:

发酵乳杆菌ME-3治疗对糖化和糖尿病并发症的影响。

2型糖尿病(T2D)会诱发与糖基化相关的器官损害,以及其他代谢途径。尽管已经测试了减少糖基化产物形成和影响的治疗策略,但结果仍然模棱两可。已经提出了使用益生菌的抗糖尿病疗法,但尚未见到其对糖化作用的影响。在此,研究了细菌菌株发酵乳杆菌ME-3对T2D小鼠模型中糖化和T2D相关并发症的影响。
更新日期:2020-02-17
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