Abstract The purpose of this study was to prepare a novel Clay Bio-Polymer Nanocomposite (CBPN) films by mixing polymer (chitosan, C) with exfoliated nanoclay (kaolinite, k). DRX has shown that the mechano-chemical treatment of kaolinite allows its exfoliation and the significant reduction of its particles size. Physicochemical properties namely thickness, water solubility, color, light transmission and transparency of the films were studied. Fourier transform infrared analysis (FTIR) was to study the interaction between chitosan and kaolinite. Differential scanning calorimetry (DSC) scans showed that the transition temperature (Tg) of films depends on the film's composition. The surface morphology of the films was also studied by scanning electron microscopy (SEM). Results showed that water solubility (Ws) decrease with the increase of the amount of clay. In addition, the presence of clay in the said films increases the mechanical strength. All prepared films were tested for their antimicrobial activities against gram-positive and gram-negative bacteria (strain). It was found that all CBPN films showed good inhibitory activity against all the tested bacteria. The above analysis suggested that the CBPN films could be used as potential candidates for therapeutic application.

中文翻译：

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壳聚糖-高岭石纳米复合材料的制备、表征、力学和阻隔性能研究

摘要 本研究的目的是通过将聚合物（壳聚糖，C）与剥离的纳米粘土（高岭石，k）混合来制备新型粘土生物聚合物纳米复合材料（CBPN）薄膜。DRX 已经表明，高岭石的机械化学处理可以使其剥落并显着减小其粒径。研究了薄膜的物理化学性质，即厚度、水溶性、颜色、透光率和透明度。傅里叶变换红外分析 (FTIR) 用于研究壳聚糖和高岭石之间的相互作用。差示扫描量热法 (DSC) 扫描表明薄膜的转变温度 (Tg) 取决于薄膜的组成。还通过扫描电子显微镜 (SEM) 研究了薄膜的表面形貌。结果表明，水溶性(Ws)随着粘土量的增加而降低。此外，所述膜中粘土的存在增加了机械强度。测试所有制备的薄膜对革兰氏阳性菌和革兰氏阴性菌（菌株）的抗菌活性。发现所有CBPN膜对所有测试细菌均显示出良好的抑制活性。上述分析表明 CBPN 薄膜可作为治疗应用的潜在候选者。