The use of protein nanostructures can be widely applied in medical devices and biomaterials. However, the synthesis of photothermic bovine serum albumin (BSA) microfibers remains a challenge. In this study, novel protein microfibers ([email protected]@Au) with bacterial filtration abilities were developed for use in inactivating bacteria under near-infrared (NIR) irradiation. Three types of [email protected] microfibers were fabricated through the assembly of proteins with M²⁺ (Fe²⁺, Cu²⁺, Mn²⁺)/Na₂S and the assistance of dopamine (DA). These were further decorated with gold nanoparticles to produce [email protected]@Au microfibers, which exhibited a filtering capacity of 1 × 10⁸ CFU bacteria per milligram, and obvious antibacterial effects at concentrations of 0.5 mg/mL. This paper presents a method that can be used in the functional micro-crystallization of proteins and the development of new types of protein fibers that can be employed in bacteria filtration and photothermal killing.

蛋白质纳米结构的使用可广泛应用于医疗设备和生物材料。然而，光热牛血清白蛋白（BSA）超细纤维的合成仍然是一个挑战。在这项研究中，具有细菌过滤能力的新型蛋白质微纤维（[Au]）被开发用于在近红外（NIR）辐射下灭活细菌。通过具有M ²⁺（Fe 2 ⁺，Cu 2 ⁺，Mn ₂ ⁺）/ Na ₂ S的蛋白质的组装和多巴胺（DA）的辅助作用，制造了三种类型的[受电子邮件保护的]超细纤维。将它们进一步用金纳米颗粒修饰，以生产[电子邮件保护] @Au超细纤维，其过滤能力为1×10 ⁸每毫克CFU细菌，浓度为0.5 mg / mL时具有明显的抗菌作用。本文提出了一种可用于蛋白质功能微晶化的方法，以及可用于细菌过滤和光热杀灭的新型蛋白质纤维的开发方法。