Bioelectrocatalysis is a green, sustainable, efficient method to produce value-added chemicals, clean biofuels and degradable materials. As an alternative approach to modern biomanufacturing technology, bioelectrocatalysis fully combines the merits of both biocatalysis and electrocatalysis to realize the green, efficient production of target products from electricity. Here, we review the development status of bioelectrocatalysis, discussing the current challenges and looking toward future development directions. First, we detail the structure, function and modification methods of bioelectrocatalysis. Next, we describe the mechanism of electron transfer, including mediated electron transfer and directed electron transfer. Third, we discuss the impact of the electrode on bioelectrocatalysis. Then we analyse and summarize the application of bioelectrocatalysis methods in the production of chemicals, biofuels and materials. Finally, we detail future developments and perspectives on bioelectrocatalysis for electrosynthesis.

生物电催化是一种绿色，可持续，有效的方法，可生产增值化学品，清洁的生物燃料和可降解材料。作为现代生物制造技术的替代方法，生物电催化充分结合了生物催化和电催化的优点，从而实现了绿色高效地用电生产目标产品。在这里，我们回顾了生物电催化的发展现状，讨论了当前的挑战并展望了未来的发展方向。首先，我们详细介绍了生物电催化的结构，功能和修饰方法。接下来，我们描述电子转移的机制，包括介导的电子转移和定向电子转移。第三，我们讨论电极对生物电催化的影响。然后，我们分析并总结了生物电催化方法在化学药品，生物燃料和材料生产中的应用。最后，我们详细介绍了生物合成用于电合成的未来发展和前景。