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A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus.
Archives of Virology ( IF 2.7 ) Pub Date : 2020-01-25 , DOI: 10.1007/s00705-019-04488-3 Yan Wang 1, 2 , Xuejiao Cui 1 , Xu Chen 2 , Shixing Yang 2 , Yu Ling 2 , Qianben Song 2 , Su Zhu 2 , Luying Sun 2 , Chuang Li 2 , Yu Li 1 , Xutao Deng 3, 4 , Eric Delwart 3, 4 , Wen Zhang 2
Archives of Virology ( IF 2.7 ) Pub Date : 2020-01-25 , DOI: 10.1007/s00705-019-04488-3 Yan Wang 1, 2 , Xuejiao Cui 1 , Xu Chen 2 , Shixing Yang 2 , Yu Ling 2 , Qianben Song 2 , Su Zhu 2 , Luying Sun 2 , Chuang Li 2 , Yu Li 1 , Xutao Deng 3, 4 , Eric Delwart 3, 4 , Wen Zhang 2
Affiliation
Using viral metagenomics, the complete genome sequence of an infectious bronchitis virus (IBV) strain (named ahysx-1) from a fecal sample from a healthy chicken in Anhui province, China, was determined. The genome sequence of ahysx-1 was found to be very similar to that of IBV strain ck/CH/LLN/131040 (KX252787), except for the spike gene region, which is similar to that of a turkey coronavirus strain (EU022526), suggesting that ahysx-1 is a recombinant. Recombination analysis and phylogenetic analysis based on the genomic sequences of ahysx-1 and other related strains confirmed that ahysx-1 appears to be a recombinant resulting from a recombination event that occurred between a chicken coronavirus and a turkey coronavirus. Further studies need to be performed to determine whether this recombinant IBV strain is pathogenic and whether it is transmitted between chickens and turkeys.
更新日期：2020-01-26
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