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Preparation of novel azidopyrazole derivatives with anticipated cytotoxic and antimicrobial activities
Journal of Heterocyclic Chemistry ( IF 2.4 ) Pub Date : 2020-01-24 , DOI: 10.1002/jhet.3747
Ewies F. Ewies, Marwa El‐Hussieny, Naglaa F. El‐Sayed, Mohamed El‐Shazly, Yu‐Cheng Chen, Yi‐Chang Liu

The reactions of azidopyrazole with some of primary amines and active methylene compounds were studied. Structures of the prepared compounds were identified using spectroscopic techniques. The reactions mechanisms were also proposed. The cytotoxic and antimicrobial activities were also examined for the newly synthesized compounds.

中文翻译:

具有预期的细胞毒和抗菌活性的新型叠氮吡唑衍生物的制备

研究了叠氮吡唑与某些伯胺和活性亚甲基化合物的反应。使用光谱技术鉴定了所制备化合物的结构。还提出了反应机理。还检查了新合成化合物的细胞毒性和抗微生物活性。
更新日期:2020-01-24
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