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Collagen-targeted MRI contrast agent for liver fibrosis detection.
Nature Reviews Gastroenterology & Hepatology ( IF 65.1 ) Pub Date : 2020-01-24 , DOI: 10.1038/s41575-020-0266-z
Paul Kennedy 1 , Bachir Taouli 1
Affiliation  

A novel MRI gadolinium-based contrast agent designed to bind with collagen, a key component in liver fibrosis progression, provides direct quantification of collagen deposition in several preclinical liver disease models. This tool could have large implications in clinical diagnosis and drug trials.

中文翻译:

针对胶原蛋白的MRI造影剂,用于肝纤维化检测。

一种新型的基于MRI ado的造影剂,旨在与胶原蛋白结合,胶原蛋白是肝纤维化进程中的关键组成部分,可直接量化几种临床前肝病模型中胶原蛋白的沉积。该工具可能对临床诊断和药物试验产生重大影响。
更新日期:2020-01-24
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