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Complications of Antenatal Corticosteroids in Infants Born by Early Term Scheduled Cesarean Section.
Diabetes Care ( IF 16.2 ) Pub Date : 2020-01-23 , DOI: 10.2337/dc19-2126
Katharine Gupta 1 , Rohit Rajagopal 1, 2 , Felicia King 3 , David Simmons 2, 4
Affiliation  

OBJECTIVE To compare neonatal hypoglycemia and respiratory morbidity rates in pregnancies complicated by diabetes following early term scheduled cesarean section (ETSCS) with and without maternal corticosteroid administration. RESEARCH DESIGN AND METHODS A retrospective cohort study of women with any form of diabetes in pregnancy undergoing ETSCS were included. Primary outcomes were admission rates to the neonatal intensive care unit (NICU) for Respiratory Distress Syndrome (RDS)/Transient Tachypnea of the Newborn (TTN) and/or neonatal hypoglycemia. RESULTS NICU admission rates for neonatal hypoglycemia were significantly higher (24.2% vs. 4.4%, P = 0.003), and RDS/TTN rates were nonsignificantly higher (15.2% vs. 7.2%, P = 0.209) following corticosteroid administration. CONCLUSIONS Corticosteroids were not beneficial among women with any form of diabetes in pregnancy undergoing ETSCS and, indeed, may be harmful. In our hospital, we have ceased the use of corticosteroids for women under these circumstances.

中文翻译:

早期计划剖宫产婴儿产前皮质类固醇的并发症。

目的比较妊娠合并糖尿病的新生儿低血糖和呼吸系统发病率在早期计划剖宫产 (ETSCS) 后给予和不给予母体皮质类固醇的情况。研究设计和方法 一项回顾性队列研究纳入了妊娠期任何形式糖尿病患者接受 ETSCS。主要结果是因呼吸窘迫综合征 (RDS)/新生儿短暂性呼吸急促 (TTN) 和/或新生儿低血糖而进入新生儿重症监护室 (NICU) 的入院率。结果 皮质类固醇给药后新生儿低血糖的 NICU 入院率显着更高(24.2% 对 4.4%,P = 0.003),RDS/TTN 率没有显着增加(15.2% 对 7.2%,P = 0.209)。结论 皮质类固醇对妊娠期任何形式的糖尿病接受 ETSCS 的妇女没有益处,而且实际上可能是有害的。在我们医院,在这种情况下,我们已停止对女性使用皮质类固醇。
更新日期:2020-03-21
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